Microsoft Gaming is a multinational video game and digital entertainment division of Microsoft. Microsoft Gaming produces the Xbox brand of video game consoles and services, in addition to overseeing the production, game development, publishing, research and development, sales (hardware, software, and services) of Xbox and the division's three subsidiaries (publishers) worldwide. The three subsidiaries consist of: Xbox Game Studios, ZeniMax Media (Bethesda Softworks acts as publisher), and Activision Blizzard (publishing split between Activision, Blizzard Entertainment, and King), each publish games under their own respective labels. CEO Phil Spencer, who has concurrently overseen the Xbox brand since 2014, is the leader of the division.

Prior to 2022, Microsoft had several areas of video game-related product lines, including Xbox hardware, Xbox operations, and game development studios. Microsoft Gaming was created in 2022 with the announcement of Microsoft's plans to acquire Activision Blizzard to unify all of Microsoft's gaming groups within a single division. With the completion of the Activision Blizzard acquisition in 2023, Microsoft Gaming makes Microsoft the third-largest gaming company worldwide by revenue and the largest video game employer in the United States.